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DUSP22 / JSP 1

dual specificity phosphatase 22

MKPX, also known as JSP-1 for Jnk Stimulatory Phosphatase-1, belongs to the LMW-DSP subfamily of phosphatases. MKPX has been shown to have the capacity to activate the c-Jun N-terminal kinase (Jnk) signaling pathway. The activation of Jnk has been implicated in a number of important physiological processes, including embryonic morphogenesis, cell survival and apoptosis. At least two mRNA transcripts have been reported. Jnk signaling has been linked to human disease conditions, such as tumor development, cardiac hypertrophy, ischemia/reperfusion injury, diabetes, hyperglycemia-induced apoptosis, and several neurodegenerative disorders.

Gene Name: dual specificity phosphatase 22
Family/Subfamily: Protein Phosphatase , LMW-DSP
Synonyms: DUSP22, JSP 1, JKAP, JNK-stimulating phosphatase 1, LMW-DSP2, Map kinase phosphatase x, MKPX, VHX, JNK-stimulatory phosphatase-1, JSP-1, JSP1, LMWDSP2, MKP-X
Target Sequences: NM_020185 NP_064570.1 Q9NRW4

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Products
Antibodies (34)
Primary (34)
DUSP22 / JSP 1 (34)
Human (34)
Mouse (7)
Bovine (5)
Chimpanzee (3)
Horse (5)
Monkey (2)
Rabbit (5)
Zebrafish (3)
IHC (9)
IHC-P (4)
WB (27)
ELISA (13)
ICC (1)
IF (5)
IP (1)
Peptide-ELISA (2)
rabbit (27)
mouse (7)
Product Group
IHCPlus (1)
PathPlus Neuro (2)
IgG (19)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (28)
APC Conjugated (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (21)
N-Terminus (5)
Internal (3)
80-160 aa, Internal (1)
aa112-185 (1)
aa121-170 (1)
No (34)
DUSP22 / JSP 1 Antibody - Anti-DUSP22 / JSP 1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Bovine, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
DUSP22 / JSP 1 Antibody - Anti-DUSP22 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Bovine, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
DUSP22 / JSP 1 Antibody - Anti-DUSP22 / JSP 1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
DUSP22 / JSP 1 Antibody - Western blot analysis of DUSP22 expression in HCT116 (A); Raw264.7 (B) whole cell lysates.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
100 µl/$299
DUSP22 / JSP 1 Antibody - Western blot analysis of lysates from RAW264.7 and Jurkat cells, using DUSP22 Antibody. The lane on the right is blocked with the synthesized peptide.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (aa121-170) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DUSP22 / JSP 1 Antibody - Immunofluorescence analysis of MCF7 cells.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
DUSP22 / JSP 1 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
DUSP22 / JSP 1 Antibody - Staining RAW264.7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µl/$332
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DUSP22 / JSP 1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using DUSP22 Polyclonal Antibody at dilution of 1:60.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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DUSP22 / JSP 1 Mouse anti-Human Monoclonal (aa112-185) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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DUSP22 / JSP 1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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DUSP22 / JSP 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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DUSP22 / JSP 1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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DUSP22 / JSP 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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DUSP22 / JSP 1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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DUSP22 / JSP 1 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
DUSP22 / JSP 1 Antibody - Western blot analysis of extracts from Jurkat cells and RAW264.7 cells, using DUSP22 antibody.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$386
DUSP22 / JSP 1 Antibody - Western blot of Human Thyroid Tumor. DUSP22 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DUSP22 / JSP 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 34 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).