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Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Gene Name: | dual oxidase 2 |
Synonyms: | DUOX2, Dual oxidase 2, Dual oxidase-like domains 2, Flavoprotein NADPH oxidase, LNOX2, NOXEF2, p138 thyroid oxidase, TDH6, Thyroid oxidase 2, NADPH oxidase/peroxidase DUOX2, THOX2, Large NOX 2, Long NOX 2, NADPH thyroid oxidase 2, p138(TOX), p138-TOX |
Target Sequences: | NM_014080 NP_054799.4 Q9NRD8 |
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