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DSG1 / Desmoglein 1
desmoglein 1
DSG1 / Desmoglein 1 is a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
| Gene Name: | desmoglein 1 |
| Family/Subfamily: | Cadherin , not assigned-Cadherin |
| Synonyms: | DSG1, CDHF4, Cadherin family member 4, Desmoglein 1, DG1, Desmoglein-1, Desmosomal glycoprotein 1, SPPK1, DGI, DSG, Pemphigus foliaceus antigen, PPKS1 |
| Target Sequences: | NM_001942 NP_001933.2 Q02413 |
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DSG1 / Desmoglein 1
(74)
Reactivity
Human
(66)
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(10)
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(22)
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(8)
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(52)
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(42)
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(29)
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(9)
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(6)
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(1)
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monoclonal mc
(16)
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(44)
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(1)
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(4)
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(6)
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(1)
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(1)
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(6)
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(1)
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(32)
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(8)
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(7)
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(1)
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(1)
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(1)
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(1)
aa841-855
(1)
Publications
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(74)
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Cell Lysates
(1)
Plasma
(5)
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(5)
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(2)
Tag
10His, N-terminus + Myc, C-terminus
(1)
GST
(1)
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(1)
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Human
(3)
Source
E. coli
(2)
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(1)
Purification
Purified
(2)
DSG1 / Desmoglein 1 Goat anti-Human Polyclonal (aa841-855) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Dsg1-P23) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
5 ml/$700
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal (aa471-499) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal (aa145-194) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Dsg1-P124) Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
5 ml/$792
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
E. coli
10His, N-terminus + Myc, C-terminus
100 µg/$1,128; 20 µg/$721
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal (130-210 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal (aa471-499) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (aa664-763) (27B2) Antibody
Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$589
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Intracellular) Antibody
Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$737
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
IF, IHC, IP, WB
HRP Conjugated
100 µl/$982
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
IF, IHC, IP, WB
Biotin Conjugated
100 µl/$982
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
IF, IHC, IP, WB
FITC Conjugated
100 µl/$982
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
IF, IHC, IP, WB
APC Conjugated
100 µl/$982
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Concentrated) (27B2) Antibody
Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
1 ml/$703
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (27B2) Antibody
Human
Flo, IF, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (27B2) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (18D4) Antibody
Human
Flo, IF, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
DSG1 / Desmoglein 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (18D4) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
DSG1 / Desmoglein 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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