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DRPLA / Atrophin-1

atrophin 1

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Gene Name: atrophin 1
Synonyms: ATN1, B37, Atrophin 1, D12S755E, NOD, HRS, Atrophin-1, DRPLA
Target Sequences: NM_001940 NP_001931.2 P54259

Publications (1)

1
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth. Jan Krivanek, Ruslan A Soldatov, Maria Eleni Kastriti, Tatiana Chontorotzea, Anna Nele Herdina, Julian Petersen, Bara Szarowska, Marie Landova, Veronika Kovar Matejova, Lydie Izakovicova Holla, Ulrike Kuchler, Ivana Vidovic Zdrilic, Anushree Vijaykumar, Anamaria Balic, Pauline Marangoni, Ophir D Klein, Vitor C M Neves, Val Yianni, Paul T Sharpe, Tibor Harkany, Brian D Metscher, Marc Bajénoff, Mina Mina, Kaj Fried, Peter V Kharchenko, Igor Adameyko. Nature communications. 2020 September;11:4816. [Full Text Article] [PubMed:32968047] [PMC:PMC7511944] Related Antibodies: LS-C352119.

☰ Filters
Antibodies (35)
Proteins (4)
Over-Expression Lysate (2)
Primary (35)
Recombinant (2)
DRPLA / Atrophin-1 (39)
Human (35)
Mouse (14)
Rat (11)
Bovine (3)
Chicken (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Horse (3)
Monkey (6)
Pig (3)
Rabbit (6)
Xenopus (3)
IHC (2)
WB (34)
ELISA (5)
ICC (1)
IF (2)
IP (3)
Peptide-ELISA (2)
rabbit (26)
mouse (9)
IgG (15)
IgG1,k (9)
monoclonal mc (9)
polyclonal pc (26)
2C10 (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (15)
aa879-1190 (8)
N-Terminus (5)
aa38-87 (4)
50-130 aa, N-terminal (1)
aa1150-C-term (1)
aa135-180 (1)
aa81-130 (1)
No (38)
Yes (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
DRPLA / Atrophin-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
125.2 kDa
20 µg/$215
DRPLA / Atrophin-1 Antibody - Western blot analysis of Atrophin-1 expression in K562 (A); EOC20 (B); HeLa (C) whole cell lysates.
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$299
DRPLA / Atrophin-1 Antibody - Immunofluorescence of monoclonal antibody to ATN1 on HeLa cell . [antibody concentration 10 ug/ml]
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (2C10) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
DRPLA / Atrophin-1 Antibody - Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
WB
Unconjugated
100 µl/$424
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa135-180) Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
50 µl/$321; 100 µl/$403
DRPLA / Atrophin-1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DRPLA / Atrophin-1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using ATN1 Polyclonal Antibody at dilution of 1:50(×200)
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DRPLA / Atrophin-1 Antibody - Western blot of Atrophin-1 antibody
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (50-130 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DRPLA / Atrophin-1 Antibody - Western blot analysis of extracts from HeLa cells, A549 cells, K562 cells, COLO205 cells and NIH-3T3 cells, using ATN1 antibody.
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa1150-C-term) Antibody
Human
IP, WB
Unconjugated
10 µg/$295; 100 µl/$514
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
DRPLA / Atrophin-1 Antibody - Western Blot; Sample: Recombinant protein.
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DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DRPLA / Atrophin-1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DRPLA / Atrophin-1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
DRPLA / Atrophin-1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
DRPLA / Atrophin-1 Antibody - Anti-Atrophin-1 Antibody at 1:1000 dilution + HeLa whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 125 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
DRPLA / Atrophin-1 Antibody - Western blot of DRPLA / Atrophin-1 antibody.
Select
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa879-1190) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Viewing 1-25 of 39 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).