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DPYSL2 / CRMP2

dihydropyrimidinase-like 2

DPYSL2 / CRMP2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: dihydropyrimidinase-like 2
Synonyms: DPYSL2, CRMP2, CRMP-2, DHPRP2, Dihydropyrimidinase-like 2, DRP-2, N2A3, ULIP2, ULIP-2, Unc-33-like phosphoprotein 2
Target Sequences: NM_001386 NP_001377.1 Q16555

Publications (4)

1
Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates. Stratmann B, Engelbrecht B, Espelage BC, Klusmeier N, Tiemann J, Gawlowski T, Mattern Y, Eisenacher M, Meyer HE, Rabbani N, Thornalley PJ, Tschoepe D, Poschmann G, Stühler K. Scientific reports. 2016 6:37737. (WB; Human) [Full Text Article] [PubMed:27898103] [PMC:PMC5127188] Related Antibodies: LS-B3616.
2
Discovery of new membrane-associated proteins overexpressed in small-cell lung cancer. Sebahat Ocak, David B Friedman, Heidi Chen, Jamie A Ausborn, Mohamed Hassanein, Bruno Detry, Birgit Weynand, Frank Aboubakar, Charles Pilette, Yves Sibille, Pierre P Massion. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 March;9:324-36. [Full Text Article] [PubMed:24518087] [PMC:PMC4028683] Related Antibodies: LS-C198892.
3
The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal extension after spinal cord injury. Kazumichi Yagura, Hirokazu Ohtaki, Tomomi Tsumuraya, Atsushi Sato, Kazuyuki Miyamoto, Naoto Kawada, Keisuke Suzuki, Motoyasu Nakamura, Koji Kanzaki, Kenji Dohi, Masahiko Izumizaki, Yutaka Hiraizumi, Kazuho Honda. PloS one. 2020 Mar;15:e0230080. [Full Text Article] [PubMed:32155215] [PMC:PMC7064230] Related Antibodies: LS-B5657.
4
PACAP stimulates functional recovery after spinal cord injury through axonal regeneration. Tsuchida M, Nakamachi T, Sugiyama K, Tsuchikawa D, Watanabe J, Hori M, Yoshikawa A, Imai N, Kagami N, Matkovits A, Atsumi T, Shioda S. Journal of molecular neuroscience : MN. Nov;54:380-7. [Full Text Article] [PubMed:25074795] Related Antibodies: LS-B5657.
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ELISA Kits (13)
Cell-Based (1)
Cell-Based Phosphorylation (2)
Custom (4)
Sandwich (6)
DPYSL2 / CRMP2 (13)
Human (5)
Mouse (6)
Rat (5)
Chicken (1)
Monkey (1)
96-Well Microplate (3)
96-Well Strip Plate (10)
No (13)
Adherent Cell Cultures (3)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (3)
Serum (3)
Tissue Homogenates (4)
DPYSL2 / CRMP2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
DPYSL2 / CRMP2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DPYSL2 / CRMP2 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
DPYSL2 / CRMP2 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
DPYSL2 / CRMP2 ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
DPYSL2 / CRMP2 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
DPYSL2 / CRMP2 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
DPYSL2 / CRMP2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DPYSL2 / CRMP2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
DPYSL2 / CRMP2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
DPYSL2 / CRMP2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
DPYSL2 / CRMP2 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
DPYSL2 / CRMP2 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).