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Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
Gene Name: | dihydropyrimidinase |
Synonyms: | DPYS, DHPase, DHP, Dihydropyrimidinase, Hydantoinase |
Target Sequences: | NM_001385 NP_001376.1 Q14117 |
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