DPP4 / CD26

dipeptidyl-peptidase 4

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

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Products

Proteins (17)

Type

Over-Expression Lysate (2)

Recombinant (15)

Target

DPP4 / CD26 (17)

Product Group

Coronavirus Antibodies Proteins cDNAs (16)

SARS-CoV-2 Associated Proteins (16)

Publications

No (17)

Tag

6His-SUMO, N-terminus (2)

Fc (1)

Fc, N-terminus (2)

GST (1)

GST, N-terminus (1)

His (5)

His,C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (11)

Mouse (3)

Rat (2)

Source

293T Cells (1)

Baculovirus (1)

E. coli (6)

HEK 293 Cells (2)

Human Cells (1)

Human Embryonic Kidney 293 Cells (1)

Mammalian Cells (3)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (6)

Biologically Active

Biologically active (1)

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Rat DPP4 / CD26 Protein (Recombinant 6His-SUMO, N-terminus) (aa638-767) - LS-G56227

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human DPP4 / CD26 Protein (Recombinant His) (aa484-728) - LS-G13065

Source:

E. coli

Tag:

His

Molecular Weight:

29.2 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human DPP4 / CD26 Protein (Recombinant) - LS-G146676

Source:

Human Embryonic Kidney 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85.4kDa

Price:

50 µg/$997

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Human DPP4 / CD26 Protein (Recombinant GST, N-terminus) (aa352-451) - LS-G58362

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DPP4 / CD26 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65420

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

88.1 kDa

Price:

20 µg/$1,107

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Mouse DPP4 / CD26 Protein (Recombinant His) (aa631-760) - LS-G13057

Source:

E. coli

Tag:

His

Molecular Weight:

16.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse DPP4 / CD26 Protein (Recombinant His) (aa29-178) - LS-G13064

Source:

E. coli

Tag:

His

Molecular Weight:

19.5 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Rat DPP4 / CD26 Protein (Recombinant His) (aa638-767) - LS-G13067

Source:

E. coli

Tag:

His

Molecular Weight:

16.3 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Human DPP4 / CD26 Protein (Recombinant GST) (Full Length) - LS-G28244

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

114.7 kDa

Price:

2 µg/$439

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Human DPP4 / CD26 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75532

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

88.1 kDa

Price:

20 µg/$150

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DPP4 / CD26 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118290

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

88.1 kDa

Price:

100 µg/$494

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Human DPP4 / CD26 Protein (Recombinant Fc, N-terminus) - LS-G137853

Source:

Mammalian Cells

Tag:

Fc, N-terminus

Endotoxin Level:

Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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Human DPP4 / CD26 Protein (Recombinant His) - LS-G3405

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

Select

Human DPP4 / CD26 Protein (Recombinant His,C-terminus) (Asn29-Pro766) - LS-G139985

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

86.4 kDa

Price:

10 µg/$302; 50 µg/$485

Select

Human DPP4 / CD26 Protein (Recombinant Fc, N-terminus) (Asn29-Pro766) - LS-G140575

Source:

Mammalian Cells

Tag:

Fc, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

111.7 kDa

Price:

10 µg/$344; 50 µg/$584

Select

Human DPP4 / CD26 Protein (Recombinant Fc) (Asn29-Pro766) - LS-G97455

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

112 kDa

Price:

50 µg/$710

Select

Mouse DPP4 / CD26 Protein (Recombinant 6His-SUMO, N-terminus) (aa29-760) - LS-G56003

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

100 µg/$1,128; 20 µg/$721

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