DOCK4

dedicator of cytokinesis 4

DOCK4 is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

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Proteins (2)

Type

Recombinant (2)

Target

DOCK4 (2)

Publications

No (2)

Tag

GST, N-terminus (1)

His-GST (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

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Human DOCK4 Protein (Recombinant GST, N-terminus) (aa1867-1966) - LS-G61232

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DOCK4 Protein (Recombinant His-GST) (aa1-300) - LS-G25691

Source:

E. coli

Tag:

His-GST

Molecular Weight:

42.4 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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