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DOCK10 is a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described.
Gene Name: | dedicator of cytokinesis 10 |
Synonyms: | DOCK10, Dedicator of cytokinesis 10, Protein zizimin 3, Nbla10300, ZIZ3, Zizimin-3, DRIP2, KIAA0694, Zizimin3 |
Target Sequences: | NM_014689 NP_055504.2 Q96BY6 |
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