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DOC2B

double C2-like domains, beta

Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.

Gene Name: double C2-like domains, beta
Synonyms: DOC2B, DOC2BL, Double C2-like domains, beta, Doc2-beta
Target Sequences: NM_003585

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
DOC2B (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
DOC2B Protein - 12.5% SDS-PAGE of human DOC2B stained with Coomassie Blue
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Wheat Germ Extract
GST
72.27 kDa
10 µg/$479; 25 µg/$670
DOC2B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.8 kDa
20 µg/$150
DOC2B Protein - Purified recombinant protein DOC2B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.8 kDa
20 µg/$1,107
DOC2B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.8 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).