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RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration.
Gene Name: | DND microRNA-mediated repression inhibitor 1 |
Synonyms: | DND1, Dead end homolog 1 (zebrafish), Dead end protein homolog 1, RBMS4 |
Target Sequences: | NM_194249 NP_919225.1 Q8IYX4 |
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