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DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Gene Name: | dynein, axonemal, light intermediate chain 1 |
Synonyms: | DNALI1, DJ423B22.5, Hp28, p28 |
Target Sequences: | NM_003462 NP_003453.2 O14645 |
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