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DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
| Gene Name: | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| Synonyms: | DNAJB6, DnaJ-like 2 protein, HSJ2, LGMD1E, MRJ, MSJ-1, MSJ1, DJ4, DnaJ, Heat shock protein J2, HHDJ1, HSJ-2 |
| Target Sequences: | NM_005494 NP_005485.1 O75190 |
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(44)
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(44)
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DNAJB6
(44)
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(44)
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(14)
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(13)
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(3)
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(3)
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(3)
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(3)
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(3)
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(3)
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(3)
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(3)
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(41)
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(19)
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rabbit
(28)
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(16)
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(27)
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(4)
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(6)
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(2)
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(1)
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monoclonal mc
(15)
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(29)
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(1)
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(3)
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(1)
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(5)
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(4)
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(5)
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(5)
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(3)
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(23)
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aa218-247
(7)
aa36-85
(4)
aa1-116
(1)
Publications
No
(44)
DNAJB6 Mouse anti-Human Monoclonal (1A5) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
DNAJB6 Rabbit anti-Human Polyclonal (aa1-116) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$485
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
DNAJB6 Rabbit anti-Human Polyclonal (aa218-247) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DNAJB6 Mouse anti-Human Monoclonal (2C11-C1) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
DNAJB6 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
DNAJB6 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
DNAJB6 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
DNAJB6 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
DNAJB6 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
DNAJB6 Mouse anti-Human Monoclonal (OTI5B5) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$434
DNAJB6 Mouse anti-Human Monoclonal (Carrier-free) (OTI5B5) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$357
DNAJB6 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
DNAJB6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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