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Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome.
Gene Name: | doublesex and mab-3 related transcription factor 2 |
Synonyms: | DMRT2, DSXL2, Doublesex-like 2 protein, Terra-like protein, DSXL-2 |
Target Sequences: | NM_006557 NP_006548.1 Q9Y5R5 |
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