DMAP1

DNA methyltransferase 1 associated protein 1

Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

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Proteins (8)

Type

Over-Expression Lysate (6)

Recombinant (2)

Target

DMAP1 (8)

Publications

No (8)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (7)

Species

Human (5)

Source

293T Cells (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

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Human DMAP1 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G62784

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DMAP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72102

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$1,107

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Human DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91421

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$150

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Human DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91423

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$150

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Human DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91424

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$215

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DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120506

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

100 µg/$494

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DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120507

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

100 µg/$494

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DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111441

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

100 µg/$710

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