Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
DLD / Diaphorase / E3 is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.
Gene Name: | dihydrolipoamide dehydrogenase |
Synonyms: | DLD, Diaphorase, DLDH, Dihydrolipoamide dehydrogenase, E3, GCSL, Lipoyl dehydrogenase, PHE3, Lipoamide dehydrogenase, Lipoamide reductase, LAD |
Target Sequences: | NM_000108 NP_000099.2 P09622 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.