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Dipeptidyl Peptidase 3 / DPP3 is a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.
Gene Name: | dipeptidyl-peptidase 3 |
Family/Subfamily: | Protease , Metallopeptidase M49 |
Synonyms: | DPP3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl-peptidase 3, Dipeptidylpeptidase 3, Dipeptidyl peptidase 3, Dipeptidylpeptidase III, DPP III, Dipeptidyl peptidase III, DPPIII |
Target Sequences: | NM_005700 NP_005691.2 Q9NY33 |
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