DICER1 / Dicer

dicer 1, ribonuclease type III

Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

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ELISA Kits (6)

Type

Custom (3)

Sandwich (3)

Target

DICER1 / Dicer (6)

Reactivity

Human (3)

Mouse (1)

Chicken (1)

Format

96-Well Strip Plate (6)

Publications

No (6)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (3)

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Mouse DICER1 / Dicer (Sandwich ELISA) ELISA Kit - LS-F13873

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Human DICER1 / Dicer (Sandwich ELISA) ELISA Kit - LS-F7611

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human DICER1 / Dicer (Sandwich ELISA) ELISA Kit - LS-F33884

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Chicken DICER1 / Dicer (Custom ELISA) ELISA Kit - LS-F13870

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine DICER1 / Dicer (Custom ELISA) ELISA Kit - LS-F13871

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human DICER1 / Dicer (Custom ELISA) ELISA Kit - LS-F13872

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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