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Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
Gene Name: | dihydrofolate reductase-like 1 |
Synonyms: | DHFRL1, DHFRP4, Dihydrofolate reductase-like 1 |
Target Sequences: | NP_789785.1 Q86XF0 |
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