DHCR7

7-dehydrocholesterol reductase

DHCR7 is an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.

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Products

Antibodies (20)

Proteins (6)

ELISA Kits (1)

Type

Over-Expression Lysate (4)

Primary (20)

Recombinant (2)

Sandwich (1)

Target

DHCR7 (27)

Reactivity

Human (16)

Mouse (14)

Rat (7)

Application

IHC (9)

IHC-P (2)

WB (16)

ELISA (10)

ICC (5)

IF (9)

IP (1)

Peptide-ELISA (1)

Host

rabbit (20)

Isotype

IgG (19)

Clonality

polyclonal pc (20)

Format

96-Well Strip Plate (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (7)

Epitope

aa437-463 (7)

aa1-50 (1)

Publications

No (27)

Sample Type

Tissue Homogenates (1)

Tag

GST (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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DHCR7 Antibody (aa437-463) LS-C167387

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (aa437-463) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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DHCR7 Antibody (aa437-463) LS-C320825

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (aa437-463) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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DHCR7 Antibody (aa437-463, Biotin) LS-C256070

Antibody:

DHCR7 Rabbit anti-Mouse Polyclonal (aa437-463) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, ICC, IF, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DHCR7 Antibody (aa437-463, FITC) LS-C256072

Antibody:

DHCR7 Rabbit anti-Mouse Polyclonal (aa437-463) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, ICC, IF, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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DHCR7 Antibody (aa437-463, APC) LS-C256069

Antibody:

DHCR7 Rabbit anti-Mouse Polyclonal (aa437-463) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, ICC, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DHCR7 Antibody (aa437-463, Azide-free, HRP) LS-C256071

Antibody:

DHCR7 Rabbit anti-Mouse Polyclonal (aa437-463) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, ICC, IF, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

DHCR7 Antibody (aa437-463, PE) LS-C256073

Antibody:

DHCR7 Rabbit anti-Mouse Polyclonal (aa437-463) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, ICC, IF, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

Human DHCR7 (Sandwich ELISA) ELISA Kit - LS-F8217

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$730

Select

DHCR7 Antibody LS-C680378

Antibody:

DHCR7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

DHCR7 Antibody (HRP) LS-C680381

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

DHCR7 Antibody (Biotin) LS-C680377

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

DHCR7 Antibody (FITC) LS-C680380

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DHCR7 Antibody LS-C409588

Antibody:

DHCR7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

DHCR7 Antibody LS-C803784

Antibody:

DHCR7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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DHCR7 Antibody LS-C310122

Antibody:

DHCR7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

DHCR7 Antibody (HRP) LS-C541789

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

DHCR7 Antibody (Biotin) LS-C521658

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

DHCR7 Antibody (FITC) LS-C531702

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

DHCR7 Antibody (APC) LS-C513444

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

Select

DHCR7 Antibody (PE) LS-C649902

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

DHCR7 Antibody (aa1-50) LS-C762837

Antibody:

DHCR7 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

Human DHCR7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80450

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.3 kDa

Price:

20 µg/$150

Select

Human DHCR7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80452

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.3 kDa

Price:

20 µg/$150

Select

Human DHCR7 Protein (Recombinant GST) (Full Length) - LS-G28198

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.9 kDa

Price:

10 µg/$479; 25 µg/$670

Select

DHCR7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118629

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.3 kDa

Price:

100 µg/$494

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