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DGKQ
diacylglycerol kinase, theta 110kDa
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
| Gene Name: | diacylglycerol kinase, theta 110kDa |
| Family/Subfamily: | Non-Protein Kinase , Diacylglycerol kinase |
| Synonyms: | DGKQ, DAGK7, DAG kinase theta, DAGK4, Diglyceride kinase theta, DAGK, DGK-theta, Diacylglycerol kinase theta |
| Target Sequences: | NM_001347 NP_001338.2 P52824 |
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