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DGKA belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Gene Name: | diacylglycerol kinase, alpha 80kDa |
Family/Subfamily: | Non-protein Kinase , Diacylglycerol kinase |
Synonyms: | DGKA, 80 kDa diacylglycerol kinase, DAG kinase alpha, Diglyceride kinase alpha, DGK-alpha, Diacylglycerol kinase alpha, Diacylglycerol kinase, alpha, DAGK1, DAGK |
Target Sequences: | NM_001345 NP_001336.2 P23743 |
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