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DGK-IOTA / DGKI is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration.
Gene Name: | diacylglycerol kinase, iota |
Family/Subfamily: | Non-protein kinase , Diacylglycerol kinase |
Synonyms: | DGKI, DAG kinase iota, DGK-IOTA, Diacylglycerol kinase iota, Diacylglycerol kinase, iota, Diglyceride kinase iota |
Target Sequences: | NM_004717 NP_004708.1 O75912 |
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