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DGK-IOTA / DGKI

diacylglycerol kinase, iota

DGK-IOTA / DGKI is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration.

Gene Name: diacylglycerol kinase, iota
Family/Subfamily: Non-protein kinase , Diacylglycerol kinase
Synonyms: DGKI, DAG kinase iota, DGK-IOTA, Diacylglycerol kinase iota, Diacylglycerol kinase, iota, Diglyceride kinase iota
Target Sequences: NM_004717 NP_004708.1 O75912

Publications (1)

1
Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice. Victoria B Bartsch, Julia S Lord, Graham H Diering, Mark J Zylka. Genes, brain, and behavior. 2020 March;19:e12570. [Full Text Article] [PubMed:30985063] [PMC:PMC6800745] Related Antibodies: LS-C118721.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).