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Derlin-3 / DERL3
derlin 3
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.
| Gene Name: | derlin 3 |
| Synonyms: | DERL3, C22orf14, Der1-like protein 3, Derlin 3, Derlin-3, DERtrin-3, IZP6, LLN2, DER3, DERtrin 3 |
| Target Sequences: | Q96Q80 Q96Q80 |
Publications (1)
1
Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heart. Belmont PJ, Chen WJ, San Pedro MN, Thuerauf DJ, Gellings Lowe N, Gude N, Hilton B, Wolkowicz R, Sussman MA, Glembotski CC. Circulation research. 2010 106:307-16. (WB; Rat)
[PubMed:19940266]
[PMC:PMC3330119]
Related Antibodies: LS-C80661.
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Products
Antibodies
(12)
Type
Primary
(12)
Target
Derlin-3 / DERL3
(12)
Reactivity
Human
(12)
Mouse
(7)
Rat
(6)
Bat
(6)
Bovine
(6)
Chicken
(6)
Dog
(6)
Gibbon
(6)
Guinea pig
(6)
Horse
(3)
Monkey
(3)
Orangutan
(3)
Pig
(6)
Rabbit
(6)
Xenopus
(3)
Zebrafish
(6)
Application
IHC
(3)
IHC-P
(1)
WB
(12)
ELISA
(3)
Host
rabbit
(12)
Product Group
IHCPlus
(1)
Isotype
IgG
(4)
Clonality
polyclonal pc
(12)
Format
Biotin Conjugated
(2)
FITC Conjugated
(2)
HRP Conjugated
(2)
Unconjugated
(6)
Epitope
C-Terminus
(4)
aa71-120
(4)
N-Terminus
(3)
Publications
No
(11)
Yes
(1)
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
WB
HRP Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
WB
Biotin Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
WB
FITC Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
HRP Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
Biotin Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
FITC Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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