Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Gene Name: | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
Synonyms: | PREX2, DEP domain containing 2, DEP.2, DEPDC2, P-REX2 |
Target Sequences: | NM_025170 NP_079446.3 Q70Z35 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.