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May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Gene Name: | density-regulated protein |
Synonyms: | DENR, Density-regulated protein, DRP1, Protein DRP1, DRP, SMAP-3 |
Target Sequences: | AF038554 AAC02985.2 O43583 |
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