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Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy.
Gene Name: | Defensin, beta 106A |
Synonyms: | DEFB106A, BD-6, BD6, Beta-defensin 6, Beta-defensin 106, Defensin, beta 106A, DEFB-6, Defensin, beta 106, DEFB106, DEFB6, Defensin, beta 6 |
Target Sequences: | NP_689464.1 Q8N104 |
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