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DEFB1 / BD-1

defensin, beta 1

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

Gene Name: defensin, beta 1
Synonyms: DEFB1, BD1, Beta-defensin 1, BD-1, Beta Defensin 1, DEFB-1, DEFB101, Defensin, beta 1, Defensin beta, HBD-1, Beta-defensin-1, HBD1
Target Sequences: NM_005218 NP_005209.1 P60022

Publications (2)

1
Association of human beta-defensin 1 gene polymorphisms with nonsegmental vitiligo. L A Ochoa-Ramírez, D S Becerra-Loaiza, S P Díaz-Camacho, V F Muñoz-Estrada, E R Ríos-Burgueño, E Prado-Montes de Oca, H Rangel-Villalobos, J S Velarde-Félix. Clinical and experimental dermatology. 2019 April;44:277-282. [Full Text Article] [PubMed:29923320]
2
Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract. Becknell B, Spencer JD, Carpenter AR, Chen X, Singh A, Ploeger S, Kline J, Ellsworth P, Li B, Proksch E, Schwaderer AL, Hains DS, Justice SS, McHugh KM. PloS one. 2013 8:e77714. [Full Text Article] [PubMed:24204930] [PMC:PMC3804605] Related Antibodies: LS-C20902.

☰ Filters
Antibodies (70)
Proteins (18)
ELISA Kits (17)
Custom (2)
Development Kit (1)
Over-Expression Lysate (2)
Primary (70)
Recombinant (16)
Sandwich (13)
Sandwich CLIA (1)
DEFB1 / BD-1 (105)
Human (43)
Mouse (17)
Rat (14)
Bovine (9)
Cow (8)
Goat (1)
Pig (9)
IHC (9)
IHC-P (3)
WB (64)
ELISA (21)
Peptide-ELISA (3)
rabbit (68)
mouse (1)
goat (1)
Product Group
DevKit Core (1)
IHCPlus (2)
Ig (1)
IgG (19)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (69)
M4-14B-H4 (1)
1000 Wells (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (1)
96-Well Strip Plate (13)
APC (5)
APC Conjugated (5)
Biotin Conjugated (8)
Cy3 Conjugated (5)
Cy7 Conjugated (5)
FITC Conjugated (7)
HRP Conjugated (8)
PE Conjugated (6)
Unconjugated (26)
aa22-69 (16)
aa2-64 (8)
aa22-68 (8)
aa24-64 (8)
N-Terminus (5)
Internal (1)
aa1-36 (1)
aa1-5 (1)
aa18-26 (1)
aa28-34 (1)
aa28-77 (1)
aa52-68 (1)
aa53-65 (1)
No (103)
Yes (2)
Cell Culture Supernatants (2)
Cell Lysates (2)
Plasma (14)
Serum (14)
Tissue Homogenates (10)
6His-SUMO, N-terminus (1)
GST (1)
His (2)
His-GST (2)
His-S (1)
Myc-DDK (Flag) (3)
Bovine (1)
Human (11)
Mouse (3)
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Rat (1)
293T Cells (1)
E. coli (14)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (6)
Low endotoxin level (7)
Biologically active (6)
Select
DEFB1 / BD-1 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µl/$801
DEFB1 / BD-1 Antibody - Anti-DEFB1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DEFB1 / BD-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
DEFB1 / BD-1 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
4 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
DEFB1 / BD-1 Protein - The ED50 was determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/mL.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~4.2 kDa
20 µg/$319; 100 µg/$746; 1 mg/$2,551
DEFB1 / BD-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
DEFB1 / BD-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
DEFB1 / BD-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
DEFB1 / BD-1 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DEFB1 / BD-1 Rabbit anti-Mouse Polyclonal (aa22-69) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
Select
DEFB1 / BD-1 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
DEFB1 / BD-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
DEFB1 / BD-1 ELISA Kit
Select
Development Kit
1000 Wells
Human
4 - 1000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$832
DEFB1 / BD-1 Antibody - Western blot analysis of lysates from human lung, using Defensin β1 antibody.
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DEFB1 / BD-1 Rabbit anti-Human Polyclonal (aa28-77) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
DEFB1 / BD-1 Rabbit anti-Mouse Polyclonal (N-Terminus) (HRP) Antibody
Mouse
ELISA
HRP Conjugated
50 µg/$866
DEFB1 / BD-1 Antibody - Western blot analysis of Defensin beta 1 expression in HEK293T (A); mouse liver (B); rat heart (C) whole cell lysates.
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
DEFB1 / BD-1 Antibody - Western blot of DEFB1 / BD-1 antibody.
Select
DEFB1 / BD-1 Rabbit anti-Cow Polyclonal (aa2-64) Antibody
Bovine, Cow
WB
Unconjugated
100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
3.9 kDa
5 µg/$268; 20 µg/$349
DEFB1 / BD-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$816
DEFB1 / BD-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
7.42 kDa
20 µg/$150
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$860
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µl/$1,054
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µl/$1,054
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
100 µl/$1,054
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$1,054
DEFB1 / BD-1 Antibody - DEFB1 / Beta Defensin 1 antibody. IHC(P): Lung Cancer Tissue.
Select
DEFB1 / BD-1 Rabbit anti-Human Polyclonal (aa52-68) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 105 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).