Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
DEFA5 / Defensin 5
defensin, alpha 5, Paneth cell-specific
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.
| Gene Name: | defensin, alpha 5, Paneth cell-specific |
| Synonyms: | DEFA5, DEF5, Defensin, alpha 5, Defensin 5, Defensin-5, HD-5, HD5(20-94) |
| Target Sequences: | NM_021010 NP_066290.1 Q01523 |
Publications (5)
1
Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract. Shen B, Porter EM, Reynoso E, Shen C, Ghosh D, Connor JT, Drazba J, Rho HK, Gramlich TL, Li R, Ormsby AH, Sy MS, Ganz T, Bevins CL. Journal of clinical pathology. 2005 58:687-94.
[PubMed:15976333]
[PMC:PMC1770712]
2
Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H, Fellermann K, Ganz T, Stange EF, Bevins CL. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:18129-34. (IHC, WB)
[PubMed:16330776]
[PMC:PMC1306791]
3
Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues. Wehkamp J, Chu H, Shen B, Feathers RW, Kays RJ, Lee SK, Bevins CL. FEBS letters. 2006 580:5344-50. (ICC, IHC)
[PubMed:16989824]
☰ Filters
Products
Antibodies
(40)
Type
Primary
(40)
Target
DEFA5 / Defensin 5
(40)
Reactivity
Human
(36)
Mouse
(4)
Application
IHC
(8)
IHC-Fr
(2)
IHC-P
(7)
WB
(36)
ELISA
(9)
ICC
(10)
IF
(6)
IP
(8)
Host
rabbit
(22)
mouse
(18)
Product Group
IHCPlus
(2)
Isotype
IgG
(24)
IgG2b
(7)
Clonality
monoclonal mc
(18)
polyclonal pc
(22)
Clone
8C8
(6)
Format
APC
(2)
APC Conjugated
(3)
Biotin Conjugated
(6)
Cy3 Conjugated
(2)
Cy7 Conjugated
(2)
DY488 Conjugated
(1)
DY550 Conjugated
(1)
DY650 Conjugated
(1)
FITC Conjugated
(6)
HRP Conjugated
(5)
PE Conjugated
(3)
Unconjugated
(10)
Epitope
aa20-94
(19)
C-Terminus
(4)
aa59-93
(1)
Publications
No
(40)
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (8C8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (Biotin) (8C8) Antibody
Human
IF, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (DY650) (8C8) Antibody
Human
IF, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (DY488) (8C8) Antibody
Human
IF, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (DY550) (8C8) Antibody
Human
IF, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
DEFA5 / Defensin 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$485
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$492; 1 ml/$563; 2 ml/$758; 5 ml/$1,233
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (HRP) Antibody
Human
ICC, IP, WB
HRP Conjugated
100 µl/$339; 200 µl/$394; 500 µl/$577; 1 ml/$705; 2 ml/$942; 5 ml/$1,603
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (Biotin) Antibody
Human
ICC, IP, WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$520; 1 ml/$598; 2 ml/$828; 5 ml/$1,356
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$348; 200 µl/$408; 500 µl/$608; 1 ml/$758; 2 ml/$996; 5 ml/$1,725
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (APC, Cy7) Antibody
Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$506; 200 µl/$651; 500 µl/$1,156; 1 ml/$1,409; 2 ml/$1,972; 5 ml/$3,697
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (Cy3) Antibody
Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465
DEFA5 / Defensin 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$968
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (8C8) Antibody
Human
IHC, IHC-Fr, WB
Unconjugated
100 µg/$723
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
200 µl/$365
DEFA5 / Defensin 5 Mouse anti-Human Monoclonal (aa20-94) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
200 µl/$379
DEFA5 / Defensin 5 Rabbit anti-Mouse Polyclonal (aa59-93) Antibody
Mouse
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
DEFA5 / Defensin 5 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$951
DEFA5 / Defensin 5 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µl/$951
DEFA5 / Defensin 5 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
DEFA5 / Defensin 5 Rabbit anti-Human Polyclonal (aa20-94) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
Viewing 1-25
of 40
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
