DDX20 / GEMIN3

DEAD (Asp-Glu-Ala-Asp) box polypeptide 20

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

DDX20 / GEMIN3 (6)

Publications

No (6)

Tag

GST (2)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human DDX20 / GEMIN3 Protein (Recombinant GST, N-terminus) (aa725-824) - LS-G61792

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DDX20 / GEMIN3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70444

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

92.1 kDa

Price:

20 µg/$1,107

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Human DDX20 / GEMIN3 Protein (Recombinant GST) (Full Length) - LS-G32564

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

116.38 kDa

Price:

10 µg/$479; 25 µg/$670

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Human DDX20 / GEMIN3 Protein (Recombinant GST) (Full Length) - LS-G32566

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

118.6 kDa

Price:

10 µg/$479; 25 µg/$670

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DDX20 / GEMIN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100990

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

92.1 kDa

Price:

100 µg/$494

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Human DDX20 / GEMIN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87115

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

92.1 kDa

Price:

20 µg/$150

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