DDX1

DEAD (Asp-Glu-Ala-Asp) box helicase 1

Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 expression. Binds to the cyclin CCND2 promoter region. Associates with chromatin at the NF-kappa-B promoter region via association with RELA. Binds to poly(A) RNA. May be involved in 3'-end cleavage and polyadenylation of pre-mRNAs. Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB: together with archease (ZBTB8OS), acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation (PubMed:24870230). Required for HIV-1 Rev function as well as for HIV-1 replication. Binds to the RRE sequence of HIV-1 mRNAs.

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Products

Antibodies (28)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (28)

Recombinant (3)

Target

DDX1 (33)

Reactivity

Human (28)

Mouse (15)

Rat (11)

Bat (6)

Bovine (3)

Chimpanzee (9)

Dog (9)

Gibbon (9)

Guinea pig (6)

Horse (6)

Monkey (9)

Orangutan (9)

Pig (3)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (10)

IHC-P (4)

WB (27)

Flo (2)

ELISA (5)

ICC (1)

IF (6)

IP (4)

Host

rabbit (25)

mouse (3)

Product Group

IHCPlus (2)

Isotype

IgG (16)

IgG1 (2)

IgG2b,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (25)

Clone

3E5B2 (1)

3E5E2 (1)

4F6 (1)

Format

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

Unconjugated (16)

Epitope

Internal (4)

aa36-85 (4)

aa432-481 (4)

aa671-720 (4)

aa500-550 (2)

aa650-C-term (1)

Publications

No (33)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

DDX1 Antibody LS-C334806

Antibody:

DDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

DDX1 Antibody (clone 3E5B2) LS-C669516

Antibody:

DDX1 Mouse anti-Human Monoclonal (3E5B2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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DDX1 Antibody (clone 3E5E2) LS-C669515

Antibody:

DDX1 Mouse anti-Human Monoclonal (3E5E2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

DDX1 Antibody LS-C482644

Antibody:

DDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

Select

IHC-plus™ DDX1 Antibody (aa650-C-term) LS-B13982

(4.0) Rating

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa650-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

IHC-plus™ DDX1 Antibody (aa500-550) LS-B13981

(4.0) Rating

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

DDX1 Antibody LS-C766010

Antibody:

DDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

DDX1 Antibody LS-C334363

Antibody:

DDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

DDX1 Antibody LS-C665026

Antibody:

DDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

DDX1 Antibody (clone 4F6) LS-C197038

Antibody:

DDX1 Mouse anti-Human Monoclonal (4F6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

DDX1 Antibody (aa500-550) LS-C285951

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

DDX1 Antibody LS-C831974

Antibody:

DDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

DDX1 Antibody (aa671-720) LS-C31398

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa671-720) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

DDX1 Antibody (aa671-720, HRP) LS-C435928

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa671-720) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

DDX1 Antibody (aa671-720, Biotin) LS-C435927

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa671-720) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

DDX1 Antibody (aa671-720, FITC) LS-C435929

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa671-720) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DDX1 Antibody (aa36-85) LS-C101627

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa36-85) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DDX1 Antibody (aa36-85, HRP) LS-C434159

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody

Reactivity:

Xenopus, Pig, Horse, Rabbit, Mouse, Dog, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

DDX1 Antibody (aa36-85, Biotin) LS-C434158

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody

Reactivity:

Xenopus, Pig, Horse, Rabbit, Mouse, Dog, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

DDX1 Antibody (aa36-85, FITC) LS-C434157

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody

Reactivity:

Xenopus, Pig, Horse, Rabbit, Mouse, Dog, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DDX1 Antibody (aa432-481) LS-C110148

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa432-481) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DDX1 Antibody (aa432-481, HRP) LS-C434162

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa432-481) (HRP) Antibody

Reactivity:

Zebrafish, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

DDX1 Antibody (aa432-481, Biotin) LS-C434160

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa432-481) (Biotin) Antibody

Reactivity:

Zebrafish, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

DDX1 Antibody (aa432-481, FITC) LS-C434161

Antibody:

DDX1 Rabbit anti-Human Polyclonal (aa432-481) (FITC) Antibody

Reactivity:

Zebrafish, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DDX1 Antibody (Internal) LS-C345783

Antibody:

DDX1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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