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DDT / Dopamine Tautomerase

D-dopachrome tautomerase

In melanocytes, D-dopachrome tautomerase (DDT) converts D-dopachrome into 5, 6-dihydroxyindole. The amino acid sequence of DDT is 33% homologous with that of macrophage migration inhibitory factor (MIF) which has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation. Crystal structure studies have shown that DDT forms a homotrimer, while site-directed mutagenesis studies show that the N-terminal proline is important for enzymatic activity.

Gene Name: D-dopachrome tautomerase
Synonyms: DDT, D-dopachrome decarboxylase, D-dopachrome tautomerase, DDCT, Phenylpyruvate tautomerase II
Target Sequences: NM_001355 NP_001346.1 P30046

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Antibodies (59)
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DDT / Dopamine Tautomerase (86)
Human (60)
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DDT / Dopamine Tautomerase ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DDT / Dopamine Tautomerase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human prostate tissue using anti-DDT mouse monoclonal antibody.
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DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI3A11) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human prostate tissue using anti-DDT mouse monoclonal antibody.
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DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI3A11) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - Western blot testing of human recombinant protein with DDT antibody.
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DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal (aa1-118) Antibody
Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$575
DDT / Dopamine Tautomerase Antibody - IHC analysis of DDT using anti-DDT antibody. DDT was detected in paraffin-embedded section of human placenta tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-DDT Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal (aa1-118) Antibody
Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human liver tissue using anti-DDT mouse monoclonal antibody.
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DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI1B1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human liver tissue using anti-DDT mouse monoclonal antibody.
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DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI1B1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human breast tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI3B10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human breast tissue using anti-DDT mouse monoclonal antibody.
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DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI3B10) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI1A1) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI1A1) Antibody
Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-DDT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI1H3) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-DDT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI1H3) Antibody
Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI3A1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI3A1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human liver tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI1F12) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human liver tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI1F12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human liver tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (OTI2H3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded Human liver tissue using anti-DDT mouse monoclonal antibody.
Select
DDT / Dopamine Tautomerase Mouse anti-Human Monoclonal (Carrier-free) (OTI2H3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DDT / Dopamine Tautomerase Antibody - DDT antibody. IHC(P): Human Lung Cancer Tissue.
Select
DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal (aa99-118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
DDT / Dopamine Tautomerase Antibody - IHC analysis of DDT using anti-DDT antibody. DDT was detected in paraffin-embedded section of mouse small intestine tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml rabbit anti-DDT Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
Select
DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
DDT / Dopamine Tautomerase Antibody - IHC staining of FFPE human ovarian cancer with DDT antibody at 2ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
Select
DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
DDT / Dopamine Tautomerase Antibody - IHC of paraffin-embedded NCIN87 xenograft using DDT antibody at 1:100 dilution.
Select
DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal (aa1-118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
DDT / Dopamine Tautomerase Antibody - Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.
Select
DDT / Dopamine Tautomerase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 86 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).