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DDH / AKR1C1
aldo-keto reductase family 1, member C1
DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
| Gene Name: | aldo-keto reductase family 1, member C1 |
| Synonyms: | AKR1C1, 2-ALPHA-HSD, 20-alpha-HSD, Aldo-keto reductase C, Bile acid binding protein, Chlordecone reductase homolog, DDH1, Dihydrodiol dehydrogenase 2, DD1, DDH, Dihydrodiol dehydrogenase 1/2, DD1/DD2, Dihydrodiol dehydrogenase 1, H-37, HAKRC, HBAB, Indanol dehydrogenase, MBAB |
| Target Sequences: | NM_001353 NP_001344.2 Q04828 |
Publications (2)
1
Expression of aldo-keto reductase 1C23 in the equine corpus luteum in different luteal phases. Kozai K, Hojo T, Tokuyama S, Szóstek AZ, Takahashi M, Sakatani M, Nambo Y, Skarzynski DJ, Okuda K. The Journal of reproduction and development. 2014 60:150-4. (WB; Human)
[PubMed:24492656]
[PMC:PMC3999394]
Related Antibodies: LS-B6269.
2
Androgen deficiency during mid- and late pregnancy alters progesterone production and metabolism in the porcine corpus luteum. Grzesiak M, Knapczyk-Stwora K, Ciereszko RE, Golas A, Wieciech I, Slomczynska M. Reproductive sciences (Thousand Oaks, Calif.). 2014 Jun;21:778-90. (WB; Human)
[Full Text Article]
[PubMed:24429677]
[PMC:PMC4016731]
Related Antibodies: LS-B12017.
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DDH / AKR1C1 Mouse anti-Human Monoclonal (AT6D10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa22-248) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) (HRP) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) (Biotin) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) (FITC) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
DDH / AKR1C1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
DDH / AKR1C1 Mouse anti-Human Monoclonal (1B3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) (HRP) Antibody
Human, Chimpanzee, Orangutan
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) (Biotin) Antibody
Human, Chimpanzee, Orangutan
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) (FITC) Antibody
Human, Chimpanzee, Orangutan
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa2-218) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human, Monkey
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
DDH / AKR1C1 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
DDH / AKR1C1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
DDH / AKR1C1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
DDH / AKR1C1 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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