Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non-canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases.
Gene Name: | dCTP pyrophosphatase 1 |
Synonyms: | DCTPP1, DCTPase 1, CDA03, DCTP pyrophosphatase 1, RS21C6, XTP3TPA, XTP3-transactivated protein A, Deoxycytidine-triphosphatase 1 |
Target Sequences: | NM_024096 NP_077001.1 Q9H773 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.