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DCHS1 is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing.
Gene Name: | dachsous cadherin-related 1 |
Family/Subfamily: | Cadherin , not assigned-Cadherin |
Synonyms: | DCHS1, CDH25, CDHR6, Cadherin-19, Cadherin-25, Dachsous 1 (Drosophila), FIB1, Fibroblast cadherin 1, Fibroblast cadherin FIB1, Hypothetical protein FLJ11790, Fibroblast cadherin-1, KIAA1773, Protein dachsous homolog 1, Protocadherin 16, PCDH16, Protocadherin-16 |
Target Sequences: | NM_003737 NP_003728.1 Q96JQ0 |
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