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DCDC2 is a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene Name: | doublecortin domain containing 2 |
Synonyms: | DCDC2, DCDC2A, KIAA1154, Ru2, Protein RU2S, RU2S |
Target Sequences: | NM_016356 NP_057440.2 Q9UHG0 |
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