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This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans.
Gene Name: | Dendritic cell-associated nuclear protein |
Synonyms: | DCANP1, C5orf20, DCNP1 |
Target Sequences: | Q8TF63 Q8TF63 |
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