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DAZL

deleted in azoospermia-like

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: deleted in azoospermia-like
Family/Subfamily: DAZ
Synonyms: DAZL, DAZL1, DAZ-like autosomal, DAZLA, Deleted in azoospermia-like 1, SPGY-like-autosomal, DAZ homolog, DAZH, Deleted in azoospermia-like, SPGYLA
Target Sequences: NM_001351 NP_001342.2 Q92904

Publications (1)

1
Transcription Factor RFX2 Is a Key Regulator of Mouse Spermiogenesis. Wu Y, Hu X, Li Z, Wang M, Li S, Wang X, Lin X, Liao S, Zhang Z, Feng X, Wang S, Cui X, Wang Y, Gao F, Hess RA, Han C. Scientific reports. 2016 6:20435. (WB; Human) [Full Text Article] [PubMed:26853561] [PMC:PMC4745085] Related Antibodies: LS-C188293.

☰ Filters
Antibodies (18)
Proteins (6)
Over-Expression Lysate (4)
Primary (18)
Recombinant (2)
DAZL (24)
Human (18)
Mouse (10)
Rat (8)
Bovine (2)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
Pig (4)
Xenopus (1)
IHC (6)
IHC-P (1)
WB (11)
ELISA (7)
IF (5)
IP (1)
Peptide-ELISA (2)
rabbit (16)
mouse (1)
goat (1)
IgG (15)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (17)
3/11A (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Supernatant (1)
Unconjugated (12)
aa218-267 (4)
Internal (1)
aa190-280 (1)
aa260-270 (1)
aa281-295 (1)
No (23)
Yes (1)
GST (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
Select
DAZL Mouse anti-Human Monoclonal (aa281-295) (Supernatant) (3/11A) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated, Supernatant
2 ml/$932
Select
DAZL Rabbit anti-Human Polyclonal (Internal) Antibody
Xenopus, Rat, Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
DAZL Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using DAZL Antibody at dilution of 1:100
Select
DAZL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Select
DAZL Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
DAZL Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
DAZL Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
DAZL Antibody - Immunohistochemistry of paraffin-embedded rat testis using DAZL antibody at dilution of 1:100 (40x lens).
Select
DAZL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
DAZL Antibody - DAZL antibody staining of paraffin embedded Mouse Testis.
Select
DAZL Goat anti-Human Polyclonal (aa260-270) Antibody
Mouse, Bovine, Rat, Pig, Human, Monkey
IHC, Peptide-ELISA, WB
Unconjugated
100 µg/$503
DAZL Antibody - Immunohistochemistry of paraffin-embedded Rat testis using DAZL Polyclonal Antibody at dilution of 1:100 (40x lens).
Select
DAZL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
DAZL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
DAZL Antibody - Western blot analysis of DAZL using Jurkat whole cells lysates
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DAZL Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DAZL Antibody - Immunofluorescence analysis of HeLa cells using DAZL Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
Select
DAZL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
DAZL Rabbit anti-Human Polyclonal (aa190-280) Antibody
Mouse, Bovine, Rat, Human
ELISA
Unconjugated
100 µl/$450
DAZL Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DAZL Rabbit anti-Human Polyclonal (aa218-267) Antibody
Human
WB
Unconjugated
100 µl/$424
DAZL Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DAZL Rabbit anti-Human Polyclonal (aa218-267) (HRP) Antibody
Mouse, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
DAZL Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DAZL Rabbit anti-Human Polyclonal (aa218-267) (Biotin) Antibody
Mouse, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
DAZL Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DAZL Rabbit anti-Human Polyclonal (aa218-267) (FITC) Antibody
Mouse, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
DAZL Antibody - Western blot analysis of extracts of mouse testis tissue lines, using DAZL antibody.
Select
DAZL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
DAZL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
33 kDa
20 µg/$150
DAZL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.7 kDa
20 µg/$150
DAZL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
33 kDa
100 µg/$494
DAZL Protein - Purified recombinant protein DAZL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
33 kDa
20 µg/$1,107
DAZL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
35.7 kDa
100 µg/$494
DAZL Protein - 12.5% SDS-PAGE of human DAZL stained with Coomassie Blue
Select
Wheat Germ Extract
GST
58.19 kDa
2 µg/$439
Viewing 1-24 of 24 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).