DAP12

TYRO protein tyrosine kinase binding protein

DAP12 is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

☰ Filters

Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

DAP12 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

Human DAP12 Protein (Recombinant GST, N-terminus) (aa21-113) - LS-G60458

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human DAP12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80277

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.3 kDa

Price:

20 µg/$150

Select

DAP12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117405

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.18 kDa

Price:

100 µg/$494

Select

Human DAP12 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67611

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.3 kDa

Price:

20 µg/$1,107

Select

Human DAP12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80276

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.18 kDa

Price:

20 µg/$150

Select

DAP12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102555

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.3 kDa

Price:

100 µg/$494

Select

Human DAP12 Protein (Recombinant GST) (Full Length) - LS-G30808

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

38.6 kDa

Price:

10 µg/$479; 25 µg/$670

Viewing 1-7 of 7 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.