DAG1 / Dystroglycan

dystroglycan 1 (dystrophin-associated glycoprotein 1)

The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.Alpha-dystroglycan is an extracellular peripheral glycoprotein that acts as a receptor for both extracellular matrix proteins containing laminin-G domains, and for certain adenoviruses. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells. Also acts as a receptor for M.leprae in peripheral nerve Schwann cells but only in the presence of the G-domain of LAMA2, and for lymphocytic choriomeningitis virus, Old World Lassa fever virus, and clade C New World arenaviruses.Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.

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Products

Proteins (3)

Type

Recombinant (3)

Target

DAG1 / Dystroglycan (3)

Application

SDS-PAGE (1)

Publications

No (3)

Tag

GST, N-terminus (1)

His,C-terminus (1)

His-T7 (1)

Species

Human (2)

Mouse (1)

Source

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human DAG1 / Dystroglycan Protein (Recombinant His,C-terminus) (Met1-Val749) - LS-G50350

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human DAG1 consists 731 amino acids and predicts a molecular mass of 79.7 kDa.

Price:

50 µg/$348

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Mouse DAG1 / Dystroglycan Protein (Recombinant His-T7) (aa28-406) - LS-G24863

Source:

E. coli

Tag:

His-T7

Molecular Weight:

44.1 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human DAG1 / Dystroglycan Protein (Recombinant GST, N-terminus) (aa31-140) - LS-G58292

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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