DAAM1

dishevelled associated activator of morphogenesis 1

Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

DAAM1 (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human DAAM1 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G61898

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DAAM1 Protein (Recombinant His-T7) (aa1-250) - LS-G24853

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.2 kDa

Price:

10 µg/$275; 50 µg/$405; 100 µg/$647; 200 µg/$810; 1 mg/$1,887; 500 µg/$1,440; 5 mg/$2,851; 2 mg/$2,072

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Human DAAM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72790

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.3 kDa

Price:

20 µg/$1,107

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Human DAAM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93585

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.3 kDa

Price:

20 µg/$215

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DAAM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113553

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.3 kDa

Price:

100 µg/$710

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