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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
CYP7B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
| Gene Name: | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP7B1, CBAS3, CP7B, Oxysterol 7alpha-hydroxylase, Oxysterol 7-alpha-hydroxylase, SPG5A, Cytochrome P450 7B1 |
| Target Sequences: | NM_004820 NP_004811.1 O75881 |
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