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CYP7B1

cytochrome P450, family 7, subfamily B, polypeptide 1

CYP7B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.

Gene Name: cytochrome P450, family 7, subfamily B, polypeptide 1
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP7B1, CBAS3, CP7B, Oxysterol 7alpha-hydroxylase, Oxysterol 7-alpha-hydroxylase, SPG5A, Cytochrome P450 7B1
Target Sequences: NM_004820 NP_004811.1 O75881

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Products
Antibodies (17)
Primary (17)
CYP7B1 (17)
Human (17)
Bat (1)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
Pig (3)
Rabbit (3)
IHC (8)
IHC-P (5)
WB (16)
Flo (1)
ELISA (4)
IF (3)
Peptide-ELISA (3)
rabbit (12)
mouse (4)
goat (1)
IgG (5)
IgG1 (1)
IgG2a,k (1)
IgG2b (2)
monoclonal mc (4)
polyclonal pc (13)
2B11 (1)
OTI1G7 (1)
OTI7H10 (2)
Biotin Conjugated (1)
Carrier-free (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (14)
aa304-353 (4)
70-150 aa, Internal (1)
Gln127 (1)
Internal (1)
aa101-150 (1)
aa252-281 (1)
aa263-506 (1)
aa350-506 (1)
aa493-506 (1)
No (17)
CYP7B1 Antibody - Immunoperoxidase of monoclonal antibody to CYP7B1 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml]
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CYP7B1 Mouse anti-Human Monoclonal (2B11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
CYP7B1 Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with CYP7B1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CYP7B1 Rabbit anti-Human Polyclonal (aa252-281) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CYP7B1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY cyp7b1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-cyp7b1.
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CYP7B1 Mouse anti-Human Monoclonal (OTI7H10) Antibody
Human
WB
Unconjugated
100 µl/$434
CYP7B1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY cyp7b1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-cyp7b1.
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CYP7B1 Mouse anti-Human Monoclonal (aa350-506) (Carrier-free) (OTI7H10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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CYP7B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
CYP7B1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-CYP7B1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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CYP7B1 Mouse anti-Human Monoclonal (aa263-506) (OTI1G7) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
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CYP7B1 Rabbit anti-Human Polyclonal (70-150 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP7B1 Antibody - Staining LOVO cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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CYP7B1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP7B1 Antibody - Immunohistochemical analysis of Cytochrome P450 7B1 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CYP7B1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
CYP7B1 Antibody - IHC of CYP7B1 (Q127) pAb in paraffin-embedded human skeletal muscle tissue.
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CYP7B1 Rabbit anti-Human Polyclonal (Gln127) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
CYP7B1 Antibody - CYP7B1 antibody (4 ug/ml) staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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CYP7B1 Goat anti-Human Polyclonal (aa493-506) Antibody
Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
CYP7B1 Antibody - Western blot analysis of extracts from LOVO cells, using Cytochrome P450 7B1 antibody.
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CYP7B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CYP7B1 Antibody - Western blot analysis of lysates from LOVO cells, using Cytochrome P450 7B1 Antibody. The lane on the right is blocked with the synthesized peptide.
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CYP7B1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CYP7B1 Antibody - CYP7B1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP7B1 Rabbit anti-Human Polyclonal (aa304-353) Antibody
Human
WB
Unconjugated
100 µl/$424
CYP7B1 Antibody - CYP7B1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP7B1 Rabbit anti-Human Polyclonal (aa304-353) (HRP) Antibody
Rabbit, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CYP7B1 Antibody - CYP7B1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP7B1 Rabbit anti-Human Polyclonal (aa304-353) (Biotin) Antibody
Rabbit, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
CYP7B1 Antibody - CYP7B1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP7B1 Rabbit anti-Human Polyclonal (aa304-353) (FITC) Antibody
Rabbit, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).