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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.
| Gene Name: | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP3A5, Aryl hydrocarbon hydroxylase, CYPIIIA5, Cytochrome P450 3A5, Cytochrome p450 IIIa5, Cytochrome P450 HLp2, CP35, Cytochrome P450-PCN3, p450PCN3, PCN3 |
| Target Sequences: | NM_000777 NP_000768.1 P20815 |
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