CYP3A4 / Cytochrome P450 3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

CYP3A4 / Cytochrome P450 3A4 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

ELISA Kits (6)

Type

Competitive EIA (1)

Sandwich (5)

Target

CYP3A4 / Cytochrome P450 3A4 (6)

Reactivity

Human (3)

Mouse (2)

Rat (1)

Format

96-Well Strip Plate (6)

Publications

No (6)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (2)

Plasma (4)

Serum (4)

Tissue Homogenates (3)

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Human CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F8043

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F32886

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F7755

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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Rat CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F27379

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F26739

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Mouse CYP3A4 / Cytochrome P450 3A4 (Competitive EIA) ELISA Kit - LS-F28244

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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