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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.
| Gene Name: | cytochrome P450, family 2, subfamily C, polypeptide 8 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP2C8, Cytochrome P450 MP-20, CPC8, Cytochrome P450 form 1, Cytochrome P450 MP-12, MP-12/MP-20, S-mephenytoin 4-hydroxylase, CYPIIC8, Cytochrome P450 2C8, Cytochrome P450 IIC2, Cytochrome p450 IIc8, p450 form 1 |
| Target Sequences: | NM_000770 NP_000761.3 P10632 |
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