Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Gene Name: | cytochrome P450, family 2, subfamily B, polypeptide 6 |
Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
Synonyms: | CYP2B6, CPB6, CYP2B, CYP2B7P, EFVM, CYP2B7, Cytochrome p450 IIb6, p450, CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 IIB1, IIB1 |
Target Sequences: | NM_000767 NP_000758.1 P20813 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.