CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, including polycyclic aromatic hydrocarbons. Promotes angiogenesis by removing cellular oxygenation products, thereby decreasing oxidative stress, release of antiangiogenic factor THBS2, then allowing endothelial cells migration, cell adhesion and capillary morphogenesis. These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis. Plays an important role in the regulation of perivascular cell proliferation, migration, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, during angiogenesis. Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression.

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Products

Antibodies (37)

Type

Primary (37)

Target

CYP1B1 (37)

Reactivity

Human (36)

Mouse (10)

Rat (14)

Bat (3)

Bovine (4)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (1)

Pig (1)

Rabbit (3)

Sheep (1)

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Application

IHC (5)

IHC-P (4)

WB (31)

ELISA (8)

ICC (1)

IF (3)

Peptide-ELISA (2)

Host

rabbit (36)

mouse (1)

Product Group

IHCPlus (2)

Isotype

IgG (18)

IgG2b,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (36)

Clone

2F8 (1)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (21)

Epitope

aa374-516 (8)

aa200-249 (4)

aa294-343 (4)

Internal (2)

aa1-260 (1)

aa143-176 (1)

aa255-480 (1)

aa400-450 (1)

aa452-497 (1)

Publications

No (36)

Yes (1)

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IHC-plus™ CYP1B1 Antibody (aa400-450) LS-B1790

(5.0) Rating

(1) Publication(s)

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa400-450) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CYP1B1 Antibody LS-C806158

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CYP1B1 Antibody (clone 2F8) LS-C197010

Antibody:

CYP1B1 Mouse anti-Human Monoclonal (2F8) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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CYP1B1 Antibody (aa200-249) LS-C81663

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa200-249) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CYP1B1 Antibody LS-C331436

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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CYP1B1 Antibody (aa294-343) LS-C170217

Antibody:

CYP1B1 Rabbit anti-Rat Polyclonal (aa294-343) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CYP1B1 Antibody (aa255-480) LS-C407759

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa255-480) Antibody

Reactivity:

Mouse, Sheep, Bovine, Rat, Pig, Horse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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IHC-plus™ CYP1B1 Antibody LS-B15932

(4.0) Rating

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CYP1B1 Antibody (HRP) LS-C680353

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CYP1B1 Antibody (Biotin) LS-C680350

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CYP1B1 Antibody (FITC) LS-C680351

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CYP1B1 Antibody LS-C664925

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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CYP1B1 Antibody LS-C805628

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CYP1B1 Antibody (aa452-497) LS-C313726

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa452-497) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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CYP1B1 Antibody LS-C192746

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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CYP1B1 Antibody LS-C824874

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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CYP1B1 Antibody (Internal) LS-C382984

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CYP1B1 Antibody LS-C833207

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CYP1B1 Antibody LS-C765946

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CYP1B1 Antibody (aa374-516) LS-C293631

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa374-516) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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CYP1B1 Antibody (aa374-516, APC) LS-C740986

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa374-516) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• APC

• Unconjugated
• APC

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CYP1B1 Antibody (Internal) LS-C352082

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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CYP1B1 Antibody (aa1-260) LS-C358142

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa1-260) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$281; 100 µg/$400

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CYP1B1 Antibody (aa143-176) LS-C99445

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal (aa143-176) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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CYP1B1 Antibody LS-C816198

Antibody:

CYP1B1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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