CYP1A2

cytochrome P450, family 1, subfamily A, polypeptide 2

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

CYP1A2 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human CYP1A2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87486

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.2 kDa

Price:

20 µg/$150

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Human CYP1A2 Protein (Recombinant GST, N-terminus) (aa211-310) - LS-G58274

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CYP1A2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70573

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.2 kDa

Price:

20 µg/$1,107

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CYP1A2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123000

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.2 kDa

Price:

100 µg/$494

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Rat CYP1A2 Protein (Recombinant His, N-Terminal) (Val192-Glu444) - LS-G25248

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

33.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human CYP1A2 Protein (Recombinant GST) (Full Length) - LS-G28126

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.9 kDa

Price:

2 µg/$439

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Human CYP1A2 Protein (Recombinant His) (aa2-231) - LS-G15242

Source:

E. coli

Tag:

His

Molecular Weight:

26.7 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human CYP1A2 Protein (Recombinant His-GST, N-terminus) - LS-G132749

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

55kDa

Price:

10 µg/$382; 50 µg/$952; 200 µg/$1,612; 100 µg/$1,378; 1 mg/$3,041; 500 µg/$2,437; 5 mg/$6,651; 2 mg/$3,548

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