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CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
| Gene Name: | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP1A2, Aryl hydrocarbon hydroxylase, Cytochrome P(3)450, Cytochrome P450 1A2, Cytochrome P450 4, p450 form 4, p3-450, p450(PA), CP12, CYPIA2, Cytochrome p450 ia2, Cytochrome P450-P3, Dioxin-inducible P3-450 |
| Target Sequences: | NM_000761 NP_000752.2 P05177 |
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CYP1A2 Mouse anti-Human Monoclonal (2C6) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$485
CYP1A2 Rabbit anti-Human Polyclonal (aa185-320) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CYP1A2 Rabbit anti-Human Polyclonal (aa255-282) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CYP1A2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, IHC-Fr, WB
Unconjugated
100 µl/$826
CYP1A2 Mouse anti-Human Monoclonal (OTI1E12) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1E12) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP1A2 Mouse anti-Human Monoclonal (OTI7D12) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (OTI7D12) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP1A2 Mouse anti-Human Monoclonal (OTI8F1) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (OTI8F1) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP1A2 Goat anti-Human Polyclonal Antibody
Human
Func, WB
Unconjugated
500 µl/$740
CYP1A2 Mouse anti-Human Monoclonal (OTI15E2) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (OTI15E2) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP1A2 Mouse anti-Human Monoclonal (OTI1H3) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP1A2 Mouse anti-Human Monoclonal (OTI6E2) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (OTI6E2) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CYP1A2 Mouse anti-Human Monoclonal (UMAB105) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$493
CYP1A2 Mouse anti-Human Monoclonal (Carrier-free) (UMAB105) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
CYP1A2 Rabbit anti-Human Polyclonal (aa255-282) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
CYP1A2 Rabbit anti-Human Polyclonal (aa255-282) (FITC) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
CYP1A2 Rabbit anti-Human Polyclonal (aa255-282) (APC) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
CYP1A2 Rabbit anti-Human Polyclonal (aa255-282) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CYP1A2 Rabbit anti-Human Polyclonal (aa255-282) (PE) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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